The cost of living is comparable, so my disposable income actually would increase. Nothing would affect my wife as she works from home and our daughter is homeschooled at this point, so no change there either.
We just made a major move last year and actually ended up closer to family and friends than we had been. Taking this offer would put us back in a situation where we're alone. We were planning on eventually moving away from here again, anyway, but we were thinking that would be a final, permanent move and it would be to a place of our choosing.
I'm still very much up in the air about this, but it's no longer just the money I'm thinking about. Things started heating up at work and I may have to seriously consider this transfer as a means to get out of the fire and back into the frying pan.